منابع مشابه
Cryoprecipitate therapy
Cryoprecipitate, originally developed as a therapy for patients with antihaemophilic factor deficiency, or haemophilia A, has been in use for almost 50 yr. However, cryoprecipitate is no longer administered according to its original purpose, and is now most commonly used to replenish fibrinogen levels in patients with acquired coagulopathy, such as in clinical settings with haemorrhage includin...
متن کاملCryoprecipitate. Patterns of use.
The type of coagulation factors and proteins in cryoprecipitate determine the appropriate indications for its use. To determine the pattern of use at a tertiary care medical center, we performed a retrospective audit of cryoprecipitate utilization. A total of 51 patients received 88 pools of cryoprecipitate. In 39 patients, cryoprecipitate was transfused for appropriate indications: hypofibrino...
متن کاملFreeze dried cryoprecipitate: a clinical evaluation.
Freeze dried cryoprecipitate was used in the treatment of 14 patients with haemophilia A. The in vivo recovery was 91.2% which is comparable to that reported from other parts of Europe. The product was efficacious and no adverse effects were reported. Freeze dried cryoprecipitate is the high yield product of a low technology process and as such may be of value in reducing any possible shortfall...
متن کاملProduction of freeze-dried human antihaemophilic cryoprecipitate.
Concentration of factor VIII from fresh plasma by cryoprecipitation remains the basis for preparation of products used to treat haemophilia A. This paper describes the preparation of a factor VIII concentrate from small plasma pools in transfusion centres with drying facilities. The dried concentrate from one litre of plasma dissolves very well in 50 or 100 ml of distilled water and contains ar...
متن کاملThe Clinical Indications for Cryoprecipitate Use
Although the first report of a successful therapjitic transfusion for hemophilia appeared in 1840 [16], sound clinical usejof blood for this purpose paralleled the elucidation of blood group serology. Plasma fractionation, spurred mostly by the need for preservable factors came into its own around 1946 [6] and the commercial application of these techniques followed shortly thereafter. Problems ...
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ژورنال
عنوان ژورنال: Pathophysiology of Haemostasis and Thrombosis
سال: 1981
ISSN: 1424-8832,1424-8840
DOI: 10.1159/000214547